I'd suggest reinstalling MediaLab if it's not running the samples. This is MediaLab v2012.4 on Windows 7? That should be fine--at the very least to run the samples. Hmm--please let us know if an update does it! And yes, the blue-ish screen link above may help also.. but it's very odd not to be able to run ANYTHING at all with a fresh install of v2012.4 or later.