That would be a bit tougher because, although you can randomly order the questionnaire files within the greater experiment file, you can't set up skips in the exp file like you can in the que file.

With regard to Access, it really simple if all you are doing is editing the questionnaire information--it's like editing in Excel. Maybe make a copy of the file and just try it and see if you like it. I would definitely prefer it if I were working with so many items. But, hey, if it's working the way you're doing it, then maybe there is no need.