If you run the "Voice Response" setup utility from the DirectRT v2010's Tools menu--do you see a microphone input listed there? We've discovered on the machines here that if a valid sound input device is not listed then it creates a lengthy delay when DirectRT starts to run an input file. Try to use the utility to see if it can capture your test voice response times. When I selected a valid microphone input and saved the settings, DirectRT started up very quickly once again. Would be curious to know if anyone else finds this as we look for a better solution. This assumes that the delay in DirectRT happens regardless of whether it's run from within MediaLab or on its own.